During the development and progression of cancer, neoplastic cells acquire a series of genetic changes that result in drastic modifications both in how the cell responds to its environment and in the cell dynamics itself. The advances in genomic technologies and next-generation sequencing have produced a wealth of information and provided substantial insights into the pathogenesis of disease. Especially in cancer, these tools have been exceptionally useful for identifying novel signal transduction pathways, with great potential for discovering new biomarkers and therapeutic targets. However, translating these findings into a breakthrough in understanding cancer biology and the care of cancer patients remains a major challenge. 

In our lab, we have in place all the computational tools, high throughput sequencing technology, and bioinformatics and cell biology techniques needed to understand cancer biology, from genomics to cell signaling. We also want to contribute to medicine, looking for ways to make the knowledge of cellular and molecular biology of cancer generated in our laboratories useful for patients with cancer.